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HMB (beta-hydroxy-beta-methylbutyrate) is a natural substance produced in the body as a derivative of the branched LEUCINE. Not being an essential molecule can be synthesized by the body as needed and all'introito the diet. It can be used for anti-catabolic and anabolic activities that would promote the increase in lean body mass when combined with body building. Decrease, also, protein catabolism and facilitate recovery processes, would increase lean body mass when combined with weight training exercises would lower cholesterol levels, would increase muscle strength and improve performance. The mechanisms of action of HMB may be either a direct intervention in inhibiting muscle catabolism induced by the stress of exercise, or act indirectly with its deficit in muscle tissue that occurs during physical stress. Here is the idea of its supplementation with the intent of slowing the catabolism and accelerate muscle anabolism.